You may have never heard of the Paget's disease, but it is important to know it in order to understand its causes and síntomas, así as the way in which this problem can be dealt with. Thus, thenóno of the próKhimas líneas we explain everything you need to know about it.
Index
¿Whaté It's Paget's disease?
The Paget's disease named after Sir James Paget, Whoén in the toñO 1876 to be describedó for the first time. It is a disease that alsoéis not known as deforming osteitis, which refers to an alterationósize no.ñor bone and deformationón secondary that takes place after suffering this disease.
afterés of osteoporosis is the disorder óseo that occurs more frequently today, with an incidence that increases with age and that it is unusual to suffer before the 40 añyou of age. Además, it is a problem that is más frequent in the paíits nóordic, England, Europa Occidental, United States and New Zealand. In the case of Spainña, has a low prevalence, dábeing alone in a 1,5%-3% of cases in the populationón greater than 65 añyou of age.
Causes of Paget's disease
Regarding the causes of Paget's disease, The truth is that es unknown. The suffering of this disease is associated with viruses such as measlesófor rubella, although alsoéit is not understood that there is an important genetic factorétic or familiar. Además, It is common that when the disease exists, this isé affecting several members of the same family, which indicates that you caníto be transmitted by the geneética.
Sísymptoms of Paget's disease
In general, the disease does not causeíobvious symptoms that may invite the professional who is facing the Paget's disease, being in the majoríof cases discovered incidentally by elevationón of alkaline phosphatase in an anároutine lysis or a chance finding on a radiographíto that it has been requested on a patient for different reasons.
The disease can affect a single bone or several.. The bones that are affected más usually are the cráneo, spine and pelvis, although any of the bones in our body can really suffer from this problem, although it is less frequenté in others.
When we find that Paget's disease causes sísymptoms in the patient, these are due to pain, deformity, síjoint symptoms or increased vascularizationón. In this type of case, the pain is caused by the enlargement of the bone itself and the productionóNo microfractures due to poor quality bone formed. It's a pain ódeep bone that is aggravated when the person remains standing or when walking.
The deformity is produced by the remodeling and increase of the bone, and it is usual that when the tibia is affected, it bends anteriorly, causing a deformity. Other bones like the fémur or the húgrouper crouch in a lateral direction. For his part, when is the cráneo the affected, this enlarges causing a headache. If it affects several vévertebrae causes kyphosis or hump.
The sísymptoms in the joints are due to the appearanceóno osteoarthritis, and when the deformity affects prónext to the jointón occurs what is called an articulation incongruityón.
Secondly, should bear in mind that the disease can cause orthopedic complicationsétips, neurológic and cardiovascular.
DiagnóStico of Paget's disease
The presence of the sísymptoms mentioned in people older than 40 años, next to an elevationón normal numbers of alkaline phosphatase can lead to suspicion that the person suffers from the Paget's disease.
Subsequently, the condition of the disease is confirmed throughéyes of meéall image. The first explorationón to perform is the gammagrafía ósea, which provides a map of the disease, indicating witháare the bones that are affected; and then an x-ray is performed.íto of these. Además, Other tests may be required when intervention needs to be planned.ón wantúrgica.
Treatment of Paget's disease
Now that you know the causes and sísymptoms of the Paget's disease, it is necessary that you know the way in which this problem can be dealt with. The treatment seeks short-term pain relief, preventing the disease from progressing and its long-term complications. Not all patients should be treated and everything will dependá of each particular case.
In general, treatment consists of three different options, Which are the following:
- Measurements general. It is recommended to avoid being overweight, and in the event that an intervention is necessaryón wantúrgica habrá to prevent bleeding complicationságicas a través of a preventive treatment.
- Treatments Pharmacológicos. The médoctor has the possibility of prescribing the patient two types of medicines, the analésick or the antiresorptives (bisphosphonates). With these úthe latter seeks to restore and maintain in the línormal mites the excessive remodeling that occurs in the disease. in functionón of the particular case of the patient will beá the expert who has to determine whenál of the two types of medicines, if these are necessary, be the one that person should take.
- Interventionón wantúrgica. La interventionón wantúrgica se tendrá into account in certain cases, as they are:
- When a release is necessaryón wantúrgica por inclusiveón radicular, when bone growth causes compressionón in nervous tissue.
- The need for a próTotal knee or hip replacement on occasions when Paget's disease causes severe osteoarthritis.
- The tratment of algún bone that is badly deformed, which usually happens in the case of the tibia, and that thanks to the interventionón wantúallows the patient who suffers from this problem to see how the pain is reduced and at the same time that they can walk better and without many problems when moving.
